Tech Evaluation Report

Adhesive Sealant Biomaterials

The aim of this study was to compare the physical properties (tensile strength and burst pressure) of TissuePatch3 with commercially available comparator products, namely TisseelTM(Baxter), TachoSil®(Nycomed) and PleuraSealTM(Covidien). The tensile strength of TissuePatch3 was statistically greater than that of TachoSil (t- test, p=0.01), under both wet and dry conditions. The tensile strength of PleuraSeal and Tisseel could not be assessed, due to problems during sample preparation. The mean burst pressure of Tisseel was significantly lower than that of TissuePatch3 (t- test, p=0.01).

The U.S. Environmental Protection Agency’s (EPA) National Homeland Security Research Center (NHSRC) Technology Testing and Evaluation Program (TTEP) helps to protect human health and the environment from adverse impacts of terrorist acts by carrying out performance tests on homeland security technologies. TTEP recently evaluated the performance of liquid and foam decontamination technologies under vendor-specified application conditions to decontaminate test coupons prepared from the materials listed below.