M Doering

This report analyzes the US market for Medical Adhesives and Sealants in US$ Million. The major product segments analyzed are Dental Adhesives & Sealants (Denture & Orthodontic Bonding Agents, Pit & Fissure Sealants and Luting Cements, Restorative Adhesives, Tray Adhesives, and Dental Surgical Tissue Bonding Agents), and Medical Adhesives & Sealants (Surgical/Internal Medical Adhesives & Sealants, and External Medical Adhesives & Sealants). Annual forecasts are provided for the period of 2000 through 2015.

Over the past century, synthetic adhesives have largely displaced their natural counterparts in medical applications. However, rising concerns over the environmental and toxicological effects of the solvents, monomers, and additives used in synthetic adhesives have recently led the scientific community to seek natural substitutes. Marine mussel adhesive protein is a formaldehyde-free natural adhesive that demonstrates excellent adhesion to several classes of materials, including glasses, metals, metal oxides, and polymers.

US6206905

Novel methods and devices which provide enhanced mixing and application of two liquid components to form a biomaterial with minimized aerosols is achieved using air flow rates below about 1.25 liters/minute in combination with a ratio of air flow to total liquid flow of from about 150:1 up to about 1500:1. Preferably the air flow is below about 1 liter/minute and the ratio of air flow to total liquid flow is from about 200:1 to about 1200:1. The parameters are ideally suited for the spray application of components which form a surgical sealant, e.g., a fibrin sealant.